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If you have ongoing jaw pain, joint irritation, or TMJ symptoms that are not improving enough with basic care alone, you may have heard about regenerative treatment options such as PRP and PRF. These therapies are both made from your own blood and are designed to support healing inside the jaw joint and surrounding tissues.
At John H. Kim, DDS in Irvine, we focus on personalized care for TMJ and orofacial pain. That means we do not recommend treatment based on hype or trend. We evaluate your joint, your symptoms, your function, and your diagnosis first. Then we decide whether regenerative treatment belongs in your care plan and whether it should be combined with other treatment such as orthotic therapy.

What Is the Difference Between PRP and PRF?
PRP stands for platelet-rich plasma. PRF stands for platelet-rich fibrin. Both are made from your own blood and both are intended to concentrate healing components from that blood for treatment use.
The practical difference is that PRP uses an anticoagulant during preparation, while PRF does not. In the clinical material we use for this topic, that difference matters because clot formation and the fibrin matrix are part of the healing cascade. PRF was developed to allow preparation without the anticoagulant by using shorter spin times.
That is why PRP and PRF are not simply two names for the same thing. They are related, but they behave differently.
Why We Tend to Favor PRF
A helpful way to understand the comparison is this: PRP tends to act faster, while PRF tends to last longer. In the transcript source, PRP is described as more like the hare, with patients often feeling better quickly but with effects that taper sooner. PRF is described more like the tortoise, with improvement that builds over time and is more long-lasting because of its higher-density fibrin network.
That does not mean PRP has no value. It means PRF may be the better fit when the goal is more sustained support for healing in the TMJ region.
Our service materials also reflect that treatment emphasis. The practice specifically offers regenerative medicine with platelet-rich fibrin therapy to help provide optimal conditions to reduce pain, improve function, regenerate, and heal.
If you want to learn more about how regenerative care fits into broader TMJ treatment, see our regenerative TMJ therapy page and our PRF for TMJ page.
Not in a simplistic, one-size-fits-all sense. The better question is whether PRF is the better option for your diagnosis, your tissue condition, and your treatment goals.

Is PRF Always “Better” Than PRP?
What the source material supports is this: PRP can create a quicker response, while PRF may offer a slower and more durable response because of the fibrin matrix. It also supports that the practice now uses PRF in place of older regenerative options such as prolotherapy and in place of alternatives like hyaluronic acid in cases where regenerative treatment is being chosen.
So when patients ask which one is better, the answer in our office is usually framed around why we use PRF and where it may fit best, not around making blanket promises. We start with the diagnosis first.
When Regenerative TMJ Treatment May Be Considered
Regenerative treatment is not the first answer for every patient with jaw pain. TMJ symptoms can come from different problems, including joint irritation, muscle tension, sprain or strain patterns, clenching, bite instability, and other contributing issues. That is why Dr. Kim begins with a detailed history, clinical examination, and, when indicated, advanced imaging and digital records.
The transcript material describes regenerative injection use in situations involving sprain or strain of ligaments, tendons, muscles, and efforts to support loose TMJ ligaments or chronic strain at muscular attachments.
In other words, the right candidate is not “someone who has TMJ.” The right candidate is someone whose exam and diagnosis suggest that regenerative support could be useful as part of a carefully built treatment plan.
If you are still trying to understand what is causing your symptoms, start with our TMJ diagnostics and evaluation page or our TMJ consultation page.
PRF Is Often Part of a Bigger Plan
One of the most important things patients miss is that TMJ treatment usually works best when it is individualized. Some patients need orthotic therapy. Some need guided jaw exercises. Some may benefit from trigger point injections, behavioral guidance, or other conservative care. Some may be candidates for PRF.
That is why we do not treat PRF as a stand-alone sales item. We treat it as one possible tool within a specialty TMJ practice focused on jaw pain, orofacial pain, and function.
For some patients, combining regenerative treatment with bite stabilization makes more sense than using either approach alone. You can explore that on our PRF with orthotic splint therapy page and our TMJ orthotic splint therapy page.
Your first step is not choosing between PRP and PRF on your own. Your first step is getting the right diagnosis.
In our office, that process may include a detailed symptom review, a clinical exam of the temporomandibular joint, digital scanning, and, when indicated, CBCT imaging with a radiology report specific to the TMJ. After that, Dr. Kim explains the diagnosis, the reason for your symptoms, and the treatment options that make sense for your case.
That kind of evaluation matters. It helps prevent patients from chasing treatments before they understand the actual source of their pain.
Yes. The clinical source material describes these as autologous biologics, meaning they come from the patient’s own blood.
Because the source material used for this practice describes PRF as providing a more long-lasting response than PRP and specifically notes the office’s use of platelet-rich fibrin therapy in regenerative TMJ care.
Not necessarily. TMJ pain has different causes. The right treatment depends on your history, exam findings, imaging when needed, and diagnosis.
Yes. The practice offers PRF as part of a broader treatment approach that may also include intraoral orthotics and other supportive care. If you are dealing with jaw pain, joint symptoms, facial pain, or ongoing TMJ frustration, schedule a consultation with John H. Kim, DDS in Irvine. A focused evaluation can help determine whether regenerative treatment belongs in your care plan and whether PRF is the better choice for your situation.
Contact Info
17305 VON KARMAN AVE.
SUITE 204 IRVINE, CA 92614
Business Hours
Mon - Tues
9:00 am - 5:00 pm
Wednesday
Closed (at Kaiser Sleep Clinic)
Thursday
9:00 am - 5:00 pm
Friday
Closed (at Kaiser Sleep Clinic)
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